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IDO Changes the T-cell Balance in the Tumor Microenvironment

  • Broadcast in Science
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In this talk recorded at the 5th annual IO360° Summit, Dr Charles Link Jr, Newlink Genetics, addresses how IDO changes the T-cell balance in the tumor microenvironment.

This talk addresses how:

  • IDO creates local immunosuppression by increasing T regulatory cells
  • IDO often works in concert with PDL-1 mediated immunosuppression
  • IDO mediated T-cell immunosuppression leads to poor prognosis in melanoma

Save the date for the 6th annual Immuno-Oncology 360° Summit on February 26-28, 2020 at the Crowne Plaza Times Square in New York City. Learn more at www.io360summit.com