The Ageless Sisters

Heart disease patients have long been encouraged to eat more fish or take fish oil supplements containing omega-3 fatty acids. The reason? People who do, tend to live longer.

nm_salmon_100119_mn

Researchers have discovered a clue to slowing down the aging process.

Now, some say a study out this evening in the Journal of the American Medical Association might explain why.

Specifically, the researchers behind the study report that for heart disease patients, omega-3 fatty acids may protect against death and illness by slowing biological aging.

However, the findings were met with skepticism from some cardiac experts who said the study had serious limitations.

In the study, Dr. Ramin Farzaneh-Far of the University of California San Francisco and colleagues followed more than 600 men with heart disease and found those taking the most omega-3 appeared “biologically younger” — that is, the ends of their chromosomes, called telomeres, looked longer and healthier.

“Patients with the highest levels of omega-3 fish oils were found to display the slowest decrease in telomere length, whereas those with the lowest levels of omega-3 fish oils in the blood had the fastest rate of telomere shortening,” Farzaneh-Far said. “This suggests that these patients were aging faster than those with higher fish oil levels.”

Some doctors agreed that the findings seem interesting.

“Telomeres do help the body repair damage,” said Dr. Stephen Kopecky, a cardiologist at the Mayo Clinic in Rochester, Minn., who was not involved with the study. “The longer they are, the more the damage repair that can occur.”

“It’s a risk-free way of potentially extending lifespan and reducing disability,” said Dr. Michael Roizen, chief wellness officer of the Cleveland Clinic in Cleveland, Ohio.

Yet some cardiologists were quick to point out that the results are preliminary, and need to be replicated before physicians can use them in practice.

Since the study was observational and couldn’t prove cause-and-effect, “we don’t really know whether ingestion of omega-3 fatty acids resulted in this ‘benefit,’” said Dr. Steven Nissen of the Cleveland Clinic. “It remains entirely possible that individuals who consume more fish also have other favorable healthy habits. … The relationship between telomere shortening and cardiovascular health is not well established.”

This concern was echoed in a statement by a spokeswoman for the National Heart, Lung and Blood Institute, who told ABC News that while the study “shows a possible association between omega-3 fatty acids and telomere length,” it “does not show causation.”

Is It the Telomeres?

Researchers aren’t entirely sure how omega-3s stop telomeres from getting smaller. While studies have shown that omega-3s appear to be effective for patients with coronary artery disease, the underlying mechanisms are not well understood. They may protect against oxidative stress, which is a major driver of telomere shortening and aging.

But what cardiologists do know is that omega-3s have been shown to have effects on other factors that contribute to heart disease risk — a benefit that some said may have little to do with telomeres.

“We have a very good explanation already for why omega-3 fatty acids have a protective effect on heart disease,” said Dr. Cam Patterson of the University of North Carolina at Chapel Hill McAllister Heart Institute. “Omega-3 fatty acids have a potent positive impact on lipids that circulate in the blood stream and damage the heart. The effects of omega-3 fatty acids on lipids are still the best advertisement for their use to prevent heart disease.”

Original Post http://abcnews.go.com/WN/Wellness/fish-oils-omega-slow-genetic-aging-heart-patients/story?id=9606251


  1. Today's Best
  2. Top Shows
  3. Best of BTR
    1. Loading

      Death of the Information Age

      Topher Morrison talks about the death of the information age and the birth of the collaboration age and much more.

    2. Tessa Watkins on Romance

      Tessa Watkins knows that romance can be found in unexpected places, particularly when women stop searching for sizzle and embrace plain old fun.

    3. Bright Blue Gorilla:

      Robyn Rosenkrantz and Michael Glover are Bright Blue Gorilla: Filmmakers and Musicians from Los Angeles. This husband-wife duo has been traveling the world since 1990 doing concerts and making independent feature films.

    4. Comic Con Recap

      As 150,000 depart from San Diego's Comic-Con, Blogcritics recaps the weekend of panels, pressrooms and parties with three of our comic-con team. Exclusive audio clips, and the latest on new shows like Legends and Dig and the new seasons of all the top serie

    5. David Pares and The UFO Network

      David Pares is an adjunct professor at several colleges, including the University of Nebraska where he is the faculty advisor for their Mutual UFO Network student organization.

    6. Celtics Beat

      Larry H. Russell may not have a co-pilot for this week’s show. But the business class section is full.

    7. Florida Politics

      Anastasia Apa joins Southern Politics to discuss Florida politics and more.

    8. Gennady Golovkin vs Daniel Geale

      Boxing’s fastest rising star, WBA/IBO Middleweight World Champion GENNADY “GGG” GOLOVKIN who will defend his titles against two-time world champion DANIEL “The Real Deale” GEALE.

    9. Food Fights Adam Richman

      That's Entertainment host, Tammy Jones-Gibbs welcomes television personality and food enthusiast and host of the new NBC's cooking competition, "Food Fights

    10. The Great American Lobster Fest

      The New England Seafood Company, The Foxhole Chicago, Green Curtain Events and Navy Pier /SMG have partnered to launch The Great American Lobster Fest, Chicago’s first outdoor lobster and weekend music festival. 25 bands, live lobster daily, Navy Pier.

    11. Clippingbook CEO Jorge Mata

      Host Thomas White welcomes Jorge Mata, Chairman and CEO of Clippingbook, along with Neil Gaydon, President and CEO of SMART Technologies to discuss tech trends and the secrets to building a culture that supports big ideas and innovation.

    12. Filmmaker Kyle Olson

      Filmmaker Kyle Olson previews "Letters to Ashleigh," his inspirational documentary based on a true story about the senseless murder of teenager Ashleigh Love. A red-carpet premiere of this touching film is scheduled for August 9.

    13. Germany’s Fairy Tale Trail

      Visit Germany’s Fairy Tale Trail: You might wonder about the origination of your favorite Fairy Tale characters like Snow White, Red Riding Hood or Cinderella. Travel Brigade finds the answers for you as we take a journey on Germany’s Fairy Tale Trail.

    14. What If You Had A Second Chance

      Kevin Hansen is the man with over 50,000 regrets - all entrusted to him by anonymous strangers who have confessed the biggest regrets of their lives on his popular website, Secret Regrets. What is the one thing in your life that you wish you could do over?

    15. Selena Gomez Moves On

      Selena Gomez has been spotted cozying up to a sexy new mystery man after her split from Justin Bieber and we break down the details of her possible new romance.

    16. Best of Chefs

      In this episode of Travel Today with Peter Greenberg we interview the top chefs at hotels around the world.

    1. Loading

      Rodney Perry Live

      On his show, Comedian Rodney Perry covers arts and entertainment, everything from comedy and politics to music and acting, with his signature comedic slant.

    2. Saturday Mornings With Joy Keys

      Joy Keys provides her listeners with insight to improve their lives mentally, physically, monetarily and emotionally. Past guests on the show have included Meshell Nedegeocello, Blair Underwood, in addition to an impressive list of CEOs, humanitarians and authors.

    3. Small Business Unstuck

      Host Barry Moltz gets small businesses unstuck. He has founded and run small businesses with a great deal of success and failure for more than 15 years. This is a business radio show where he shares all the craziness of small business. It’s that craziness that actually makes it exciting, interesting and totally unpredictable.

    4. The Bottom Line Sports Show

      The Bottom Line Sports Show is hosted by former NBA stars Penny Hardaway, Charles Oakley, Mateen Cleaves. Tune in to get the inside scoop on what's happening in sports today.

    5. Hits Radio

      Hits Radio covers basketball, sports culture and entertainment with past guests including Jason Kidd, Robin Lundberg and Chris Herren.

    6. The Halli Casser-Jayne Show

      Listeners get an earful on The Halli Casser-Jayne Show, Talk Radio for Fine Minds. Whether it’s the current political cocktail or the latest must-read award-winning book, Halli tackles all topics and likes to stir — and sometimes shakes — things up.

    7. America's Most Haunted

      Official Internet radio show of forthcoming epic paranormal investigation book by Eric Olsen and "Haunted Housewife" Theresa Argie.

    8. World Footprints

      Award-winning World Footprints is a leading voice in socially responsible travel and lifestyle. Hosts Ian & Tonya celebrate culture and heritage and bring a unique voice to the world of travel.

    9. Football Reporters Online

      Football Reporters Online is a group of veteran football experts in the fields of coaching, scouting, talent evaluation, and writing/broadcasting/media placement. Combined, the group brings well over 100 years of expertise in sports.

    10. Small Business Roundtable

      Host John Martin interviews the nation's leading entrepreneurs and small biz experts to educate small business owners on how to be successful. Past guests have included Emeril Lagasse and Guy Kawasaki.

    11. Sylvia Global

      Sylvia Global presents global conversations pertaining to women, wealth, business, faith and philanthropy. Sylvia has interviewed an eclectic mix from CEOs and musicians to fashion designers and philanthropists including Randolph Duke and Ne-Yo.