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New developments for multiple myeloma are happening at an ever increasing pace. Dr. Ola Landgren is Chief of the Myeloma Service at Memorial Sloan Kettering Cancer Center and heavily involved in the direction of myeloma research, both nationally and internationally. In this show he will give a wrap up of the recent Rome International Myeloma Working Group meeting as well as an ASH preview (for the upcoming December conference). He will also share up and coming clinical trials at Memorial Sloan Kettering Cancer Center to incorporate these new treatments into clinical practice. Learn what new drugs will be available and how they can be used in the myeloma clinic.
Dr. Don Benson, MD, PhD of The James Cancer Center at Ohio State University is a multiple myeloma specialist with deep expertise in immunotherapy. He shares the growing and exciting world of immunotherapies in multiple myeloma - how they work and how they are opening up an exciting new set of opportunities for myeloma patients.
With the explosion in immunotherapies for multiple myeloma, we have heard there are "windows" of best and most effective use. What are those windows and when is the best time to use these new approaches? The field is ever growing and Dr. Djordje Atanackovic will share how and when to use these new tools for a myeloma patient's best care.
Thanks to our episode sponsor, Takeda Oncology
Treatment for multiple myeloma is all about the combinations. Recently we've been hearing about the "BIRD" combinations. What are they and how effective are they? Learn from Dr. Tomer Mark, MD, MSc from Weill Cornell Medical Center about this new combination and what it means for myeloma patients.
Immunotherapies are making their way into the clinic and as they do, more exciting options will be available for patients. Researchers are now studying the best possible way to leverage the standard and effective multiple myeloma treatments with ways to empower the immune system to fight myeloma. Learn what Dr. Daniel Fowler, MD of the NIH is doing to use a Th1 and Th2 immune therapy treatment in combination with stem cell transplant in an early clinical trial.
Special thanks to our Myeloma Crowd Radio episode sponsor, Amgen.
Myeloma presents itself with different features in each patient. In order to understand your disease and monitor it, you need to know which are the tests available and how often you have to get the tests done. No single test or study is adequate to tell the whole story about a patient's status, but when used together, test results can give a complete picture. Our experienced myeloma panel is talking to Dr. Joseph Mikhael about understanding your myeloma, types of diagnostic tests and their frequency.
Dr. Joseph Mikhael is a hematologist/oncologist at the Mayo Clinic in Arizona where he researches, teaches and treats multiple myeloma and related conditions. After completing medical school and residency at the University of Ottawa, he completed a second residency and fellowship at the University of Toronto and the Princess Margaret Hospital in Toronto, Ontario. At the Mayo Clinic, Dr. Mikhael is a principal investigator for clinical trials in both relapsed/refractory and newly diagnosed multiple myeloma.
The University of Pennsylvania had tremendous results with a recent clinical trial using a CAR T cell treatment targeting CD19 for a myeloma patient. The results were so impressive that some wonder if they have been able to eliminate the myeloma stem cell clone for one patient who had relapsed 9 therapies and had a high-risk genetic feature. Learn more about this success and where UPENN is going next using CAR therapy with Dr. Adam Cohen, MD, Director of Myeloma Immunotherapy at the Perelman Center for Advanced Medicine at UPENN.
Thanks to our episode sponsor, Amgen.
Could an MRI predict how a multiple myeloma patient's disease will progress and respond to treatment? Learn what Dr. Jens Hillengass, MD of the University of Heidelberg is doing to use the latest in imaging techniques to learn more about an individual patient's myeloma and what it means for their outcomes and care.
March is Myeloma Awareness month and we are exploring the allo transplant therapy route for myeloma patients in our talk with Dr. Bensinger. Why are allogeneic stem cell transplants risky for multiple myeloma patients? When does possible benefit outweigh the risks? RSVP to participate by asking a myeloma question LIVE on the talk to our panel of experts and patients. To mark the Myeloma month of awareness, we have extended our show time by 15 mins where we will have Sarah Kaufmann-Fink of MMore joining us to talk about MMores new research and crowdfunding venture.
Social media tools can be used by doctors and patients to speed the time to cure, especially for rare diseases like multiple myeloma. Learn from myeloma specialist and oncologist Dr. Mike Thompson, MD, PhD from the Aurora Health Care how he is driving social media adoption in oncology to increase the speed for the discovery of a cure and what that means in the every day lives of myeloma patients.
Special Thanks to today's episode sponsor, Takeda Oncology.
Could multiple myeloma genetics give us clues into who will respond to standard treatments and who will not? Dr. Brian Van Ness, PhD of the University of Minnestota shares his study to do just that. In a collaboration between the Unversity of Minnesota and the Mayo Clinic, Dr. Van Ness will describe his study to determine who will respond to treatment (or not) even before the treatment is given. Learn more about how standard therapies can be effectively used in this important show.
UAMS has led the way in studying the biology of myeloma cells to find new therapies. We now know that multiple myeloma patients can have a variety of types of myeloma cells at the time they are diagnosed - some with more aggressive features than others. Researchers have found that patients with several different types of myeloma cells at diagnosis seem to have early relapse and shorter survival while patients with one dominant type of myeloma cell tend to do better. Learn what Dr. Gareth Morgan, MD, FRCP, FRCPath, PhD, Dr. Niels Weinhold, PhD and Dr. Christoph Hueck are doing to find out which clones are the most aggressive and which therapies increase the mutation rate, leading to a more resistant myeloma clone.
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