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The phenomenon of limited cellular division was first observed by Leonard Hayflick, and is now referred to as the Hayflick limit.
Significant discoveries were made by the team led by Professor Elizabeth Blackburn at the University of California (UCSF).
Advocates of human life extension promote the idea of lengthening the telomeres in certain cells through temporary activation of telomerase (by drugs), or possibly permanently by gene therapy.
They reason that this would extend human life. So far these ideas have not been proven in humans.
However, it has been hypothesized that there is a trade-off between cancerous tumor suppression and tissue repair capacity, in that lengthening telomeres might slow aging and in exchange increase vulnerability to cancer (Weinstein and Ciszek, 2002).
We got an outstanding review in On Milwaukee, when the film played at the Milwaukee Film Festival. Maxim wrote a great review (while omitting ½ of the directorial team!). Also, friend of The Immortalists Patrick Brice (director of CREEP) gave us a shout out in Sac Town Magazine.
Onward and upward! http://www.facebook.com/theimmortalists
Aubrey David Nicholas Jasper de Grey is an English author and theoretician in the field of gerontology and the Chief Science Officer of the SENS Research Foundation. Aubrey de Grey, William H. Andrews http://theimmortalists.com