Getting a Handle on PK Parameters

Pharma IQ speaks to Thomas Jaki, Lecturer from Lancaster University and expert in the estimation of pharmacokinetic (PK) parameters. He outlines the key issues which must be overcome when it comes to improving the clinical trials process and the key solutions and strategies currently at the forefront. Next he discusses how to assess whether the non-compartmental approach or modelling is the best option and sets out the methods available for the non-compartmental estimation of PK parameters. He also elaborates on the methodology for testing for bioequivalence using the AUC.