DrFrankMurphy

Author of Worried Sick: A Prescription for Health in an Overtreated America Published June 2, 2008 $28.00 hardcover, ISBN 978-0-8078-3187-8

Q: You’re an eminent physician and scientist and a renowned clinician and clinical educator. In Worried Sick, you call for evidence-based medicine that demands that the care of the patient be tempered by the science that delimits clinical certainty. What compelled you to become a reformer? Do you think that your message will be controversial?

A: I never viewed myself as a reformer, only as a physician who feels compelled to bring the highest level of clinical scholarship to the bedside and to model such an approach for my students. I have taught medicine at the bedside for 40 years with the same rigor I bring to Worried Sick. Furthermore, the notion that medical practice should take advantage of whatever science has to contribute is not controversial. That notion is a tenet.

However, “evidence based medicine” has become a shibboleth rather than a process. All I am doing and all I am asking is that we closely examine the “evidence” as to its relevance to the well being of any particular patient. Worried Sick teaches how to do so, and how productive the exercise can be. The result demystifies much that is common practice, and informs the patient- physician dialogue. If the result flies in the face of common practice, it is common practice that needs reform.

Q: How do you hope Worried Sick will be used?

A: I have written Worried Sick to serve three audiences: I want to teach all how to interpret medical advice from any source and how to participate in a dialogue with anyone we choose to serve as our clinical resource. I want to establish a new standard for bedside teaching of all health care professionals. I want to inform the health care policy debate.

Overly ambitious? Certainly. Overdue? Also, certainly.

Q: Why did you decide to include a shadow chapter for each of the chapters?

A: Some of the lay readership will desire access to the details of the science that supports my assertions. In fact, I hope that all readers will feel such a need. However, all health professionals who read Worried Sick should demand ready access to such detail. After all, many of my assertions will seem counterintuitive at first blush. I would not serve the readership well without the shadow chapters and the extensive bibliography.

Q: How does this book differ from your previous work, The Last Well Person: How to Stay Well Despite the Health-Care System?

A: Worried Sick differs from The Last Well Person in many important aspects: First of all, Worried Sick picks up where The Last Well Person left off both chronologically (since the literature of the 4-year interval is emphasized) and substantively since much of the clinical science has matured. Secondly, several important issues that were barely touched upon in The Last Well Person are carefully dissected in Worried Sick. And I have gone to some length to cast the inferences in a light that is directly relevant to health policy considerations.

I have attempted to craft Worried Sick so that anyone who has read The Last Well Person will feel well served by reading Worried Sick as well. Many a medical journal club has used each of the shadow chapters in The Last Well Person as a focus and stimulus; the same journal clubs can productively return to the chapters in Worried Sick to good effect.

Q: Why is it so difficult for the average patient to advocate for himself or herself in the contemporary health-care delivery system?

A: It is not just the “average” patient who has such difficulty. We all do, even those of us with medical expertise. The role of the patient is one of inherent vulnerability. We must countenance the probing of another human being into aspects of our life story that we hold so very dear. We need to trust our “provider.” We reserve a special pedestal for our “provider.” We will feel a great deal of disquiet if that trust is lacking. “Health care” is a philosophy. It may be informed by science, but it is always a philosophy.

Today, trustworthiness is assaulted by a “health care delivery system” that places little value on these human interactions and great value on “efficiency” and profitability. Neither the patient nor the practitioner is a primary “stakeholder” any longer.

Worried Sick leaves no doubt as to this emperor’s clothing and tailor.
Q: What is “Type II medical malpractice”?

A: We all know about “medical malpractice.” It’s when appropriate medical care is administered inappropriately. I call this Type I medical malpractice. In Worried Sick I repeatedly illustrate another form of medical malpractice, the practice of doing the unnecessary very well. This Type II medical malpractice demands recognition and expunging as much as Type I medical malpractice. No one would argue. But you will learn in Worried Sick that some of the most technologically sophisticated and expensive interventions, interventions for which a great deal of training is required and about which there is exuberant institutional pride, interventions to which you and your neighbor are likely to submit are shining examples of Type II medical malpractice.

Q: What does it mean to be well, and what makes one’s sense of well-being so fragile?

A: To be well is to have a sense of invincibility, a sense that we can cope with much that life throws in our path. This sense of invincibility is repeatedly challenged; none of us lives long without such symptoms as backache, heartache, headache, heartburn and much else. Furthermore, often these challenges from within are confounded by challenges from without in our lives at home and at work.

To be well is never to be taken for granted. To feel well requires well tuned coping mechanisms.

Q: What keeps us from having a rational health-care delivery system? A: The simple answers: the profitability of the abomination we currently underwrite and the

marketing that fools us all.

Q: What is the relationship between socioeconomic status (ses) and longevity?

A: In the resource advantaged world, medicine has little to offer for the longevity of the population. Yes, we save lives. We save the lives of individuals with acute infectious diseases, some with trauma, some with acute illnesses such as appendicitis, and the like. But this saving of lives advantages a tiny, albeit crucial, percentage of the public. Furthermore, the classic “risk factors” such as some magnitude of BMI or of insulin resistance or of cholesterol are “risk factors” indeed, but the risk they represent is measurable in terms of months of longevity for the public. The majority of your risk for not living to a ripe old age is captured by 2 questions: Are you comfortable in your socioeconomic status? And are you comfortable in your employment? A negative answer puts years of longevity at risk.

We don’t understand the biological correlates of these real-world risk factors, though there are clues. But we do know they subsume all that is marketed as important including lowering you cholesterol or treating your adult onset diabetes.

Q: Why is “iatrogenicity” a word that we, as health consumers, should be more familiar with?

A: Iatrogenicity means diseases and illnesses caused by doctors. Much is made of iatrogenicity in the lay press, usually in terms of medical errors. I do not dismiss or excuse such errors. However, Worried Sick focuses on errors of commission that are not considered medical errors in the tradition of “Type I” medical malpractice. Worried Sick considers the personal price you pay if you learn that a PSA, or mammogram or cholesterol or bone mineral density is not up to snuff. You will learn whether this inference is a valid indicator of important consequences and whether the interventions based on this inference actually advantage you. If they don’t, you are left with an altered perception of your health and whatever toxicities you might derive from ineffective treatment. That is also iatrogenicity.

Q: You consider interventional cardiology and cardiovascular surgery the cash cows of the American health care delivery system. Why? Don’t many patients feel that they have benefited from cardiovascular surgery?

A: Interventional cardiology and cardiovascular are the leading “health care” expenses. The cash that flows on their watch underwrites medical centers and their administrators, many manufacturers, most insurance companies, and all the other purveyors including the medical “providers.” Furthermore, the cash that flows rewards the various purveyors obscenely generously. It would make sense if all this actually benefited the patients. It’s a scam.

However, no one can go before an American physician with anything approaching heart disease without finding themselves in the interventional vortex. No one can survive this vortex without assuming they survived as a result and not despite all that was done.

A read through Worried Sick might spare you, if you have the courage of your conviction and learn to ask the telling questions.

Q: You note that “normal body weight” is a social construction, as is osteopenia. How so? What’s harmful about this kind of thinking?

A: How about some reality testing? We will all die. The issue is not why, but when. We will all age. The issue is not why, but how elegantly.

A concomitant of aging is loss of bone mineral density. A risk factor for death is a body weight beyond “normal.”

In the first instance, we need to know if a diminished bone mineral density represents a meaningful hazard for our own quality of aging. In the second instance, we need to know if “obesity” is a meaningful risk for death before my time.

Read Worried Sick. Short of extremes, in both instances the hazard is not worth worry, let alone any potential for adverse effects of drugs or of being labeled abnormal.

Q: What fallacies surround the conclusions drawn from the Harvard Nurses’ Health study?

A: Let’s talk about hubris. Do you really think you can generate meaningful data about such lifestyle factors as nuances of dietary preferences over decades? Do you really think we can measure tiny differences in large data sets reliably, or meaningfully? Read Worried Sick before answering.

Q: In your opinion, did Katie Couric’s decision to have a televised colonoscopy do the general public more harm than good? Do the benefits of undergoing a colonoscopy outweigh the risks of the screening?

A: Katie Couric’s husband died long before his time and that is truly sad. Colonoscopy at a very early age might have saved his life.

However, death before your time from colon cancer is quite rare. We would do more harm performing colonoscopy on healthy young people from complications of the procedure than we would “do good” in sparing a rare individual (one without a family history of colon cancer) death before their time from colon cancer.

Likewise, finding colon cancer in the elderly is not likely to benefit the elderly. They are more likely to die with colon cancer but from something else.

Therein lays the debate.

A single colonoscopy sometime in your 50s probably has a tolerable risk/benefit ratio. Probably. I discuss the “probably” in detail in Worried Sick.

Q: How difficult do you think it will be to get patients to accept that it matters little what one dies of as long as it’s one’s time to die anyway? Why are we so resistant to the idea that we are mortal and likely to live only until about the age of 85?

A: Americans today are taught that there is a scientific solution to all problems. We have no sense of mortality. Furthermore, this sophism is highly profitable for many who promote it, and highly seductive to all who listen. I wrote Worried Sick to promote reality testing.

Q: Why do you think that many women would be better off if their breast cancer was never detected? Why do you think that mammography offers so little of value to women screened?

A: I fervently hope that some day we will have the ability to detect the breast cancer that is likely to kill a woman before her time. I would applaud such a screening modality and demand that we educate all women to be screened.

Mammography in all its current guises fails miserably in this regard. All it accomplishes is widespread anxiety, enormous numbers of biopsies that are irrelevant, and a great transfer of wealth.

Q: According to Worried Sick, most male physicians over the age of 50 have had Prostate Specific Antigen screening (PSA). You are one of the few who have not. Why won’t you submit to this test that’s considered almost a rite of passage?

A: PSA screening is a very flawed test. You never want to do screening unless the test detects a disease that should be treated. PSA screening is problematic. Firstly, by my age all men have prostate cancer though nearly all will die with prostate cancer and not from prostate cancer. PSA screening is very poor at distinguishing those who will die from prostate cancer from those who will die with it. As I say repeatedly, I will die but I am more concerned about when then how. PSA screening offers no solace.

So why not remove all aging prostates? Or, why not remove all aging prostates which happen to consistently secrete a lot of PSA? Very few would die with prostate cancer and almost none from prostate cancer. However, nearly all would die at the same time if they had not been subjected to the surgery. Furthermore, about 15% of these “saved” men would spend the rest of their life incontinent and 15% would be troubled by their impotence.

No thank you.

Q: You say that “To be well is not to be free of physical and emotional symptoms or to be spared physical and emotional challenges. . . . To be well is to be able to cope effectively with the challenges.” As a physician, how difficult is it for you to get patients and their families to accept this definition of wellness?

A: Medicine is a practice based on trust and trust grows out of many interactions over time. Mine is a subspecialty practice focusing on chronic illness. My patients know me. We can discuss issues such as these without discomfort. My patients are never “rheumatoids”; they are people who happen to be confronting rheumatoid arthritis. There should be no “survivors” or “diabetics” or “hypertensives” or the like—only people with an illness-colored narrative of life. Such individuals are comfortable discussing the role of coping in feeling well.

Q: It can be very stressful to resist a health practitioner’s advice. One can be afraid of displeasing one’s doctor by refusing to take a test or to fill a prescription. How would you advise such a patient? Should one find another doctor?

A: Yes, one should find another doctor. I wish that wasn’t easier said than done. It takes 20 seconds to write a prescription but 20 minutes not to. Physicians would like to have the 20 minutes. In our “health care delivery system”, they would be punished fiscally for doing so. That’s why Worried Sick is designed to inform the policy debate.

Q: Why do most patients resist simply coping on their own when symptoms arise? Why is it difficult to feel that one can be well without the supervision of a physician?

A: Some of us go through life feeling vulnerable. For some of these, this uncertainty is the product of the child rearing style of their parents. That’s not a condemnation. It’s an observation.

All of us are aggressively medicalized. Billions of dollars are spent in marketing vulnerability. Sleeplessness, leg twitching, fatigue, sadness, belching, being a brat, and so much more is medicalized so that taking a pill is sensible. Life in general is medicalized; it’s a minefield. Fish is good for you unless there’s too much mercury. This year if you feed your child margarine you’re a criminal; last year it was butter. The billions spent on neutraceuticals, biologics, and supplements advantage no consumer. It’s endless, unless you learn to ask the critical question. Is this evidence based health promotion or simply marketing?

Q: Why are alternative therapies so appealing?

A: I have two inter-related answers: Whenever medicine gets as outrageous as it is today, and was a century ago, “people” find safer ports in their storms. Furthermore, in our complex society, more and more we need a port in the storm. That doesn’t mean the alternative is salutary. As discussed in detail in Worried Sick, almost no “modality” purveyed as alternative withstands scientific testing. Alternative therapy buys you another friend with another mind set bolstered by another bundle of untested and often fatuous theories. Just because an alternative port is less likely to do you physical harm doesn’t mean the experience is trivial. It is guaranteed to change your sense of self, your idioms of distress, your mode of coping, and your narrative of illness forever. Caveat emptor.

Q: You state that you know of no higher calling that teaching medicine at bedside, and yet, you acknowledge that you feel like an anachronism in your own and other American hospitals. Do you think that other physicians feel the same way?

A: I know of many, and that many feel the same way. The national emphasis is on “throughput”. Patient care is “managed” with efficiency (profitability) the goal. There are few Socratic sessions, almost no references in charts, little argument between consulting groups, nor are

patients admitted for other than “reimbursable” goals. The vaunted clinical scholarship of mid- century is barely a ghost.

Q: What’s the difference between the Quality Movement in health care and the Effectiveness Movement?

A: There is a major emphasis on efficiency and “quality” as cures for the inadequacies of the American health care delivery system. There is no argument. However, efficiency and quality is the cart; effectiveness is the horse. If the treatment is ineffective, who cares how well or efficient it is delivered. That’s why CMS (Center for Medicare Services) studies of improved quality of care for in-patient interventional cardiology demonstrate no improvement in outcome. The “quality” of ineffective care was improved.

Q: Which groups have been most responsive to your message?

A: I’ve been asked to deliver this message to many groups: Congress, leaders of industry, “health” insurance and academic health center administrators, and many academics here and abroad. All are receptive to the message. However, any would pay a great personal and organizational price to act on it. After all some 17% of the GDP is invested in the status quo, an investment that captures many with its largesse. It would require a popular mandate for anyone to act. Worried Sick is written to incite such a mandate.

Q: How optimistic are you that reforms that you propose will be adopted?

A: I have no doubt they will be adopted. I have no doubt I will not live to see it. I have no doubt that between now and then we will have an ever more abusive “health care delivery system” until it implodes. Worried Sick is my attempt to circumvent the last.

### This interview may be reprinted in part or in its entirety with the following credit:
An interview with Nortin M. Hadler, M.D., author of Worried Sick: A Prescription for Health in an Overtreated America, University of North Carolina Press, June 2, 2008). The text of this interview is available at www.ibiblio.org/uncp/media/hadler.

PUBLISHING DETAILS

ISBN 978-0-8078-3187-8, $28.00 hardcover Approx. 392 pp., 12 tables, supplementary readings, bibl., index Publication date: June 2, 2008 The University of North Carolina Press 116 South Boundary Street, Chapel Hill, NC 27514-3808 1-800-848-6224 (orders), 919-966-3829 (fax)

CONTACTS Publicity: Gina Mahalek, 919-962-0581; gina_mahalek@unc.edu Sales: Michael Donatelli, 919-962-0475; michael_donatelli@unc.edu Rights: Vicky Wells, 919-962-0369; vicky_wells@unc.edu


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